Possibly having the coolest artwork alone, Omega Ace has a very powerful ability. You'll only really want to use it at range 1 to ensure your 3-dice attack will make a dent and remember, the ability turns even blanks to critical hits. It will take a lot of practice and coordination from other squad mates to ensure you have a focus token and a target lock (this works perfectly with the Targeting Synchronizer tech upgrade).
You can be sure your opponent won't want Omega Ace sticking around too long, so be sure something else looks more menacing than him in your list.
Lastly, try to having another higher pilot skill than Omega Ace to ensure the shields of the enemy are down before delivering the critical system.